Scientists have identified specific biological mechanisms that cause aging people to gain weight… no matter how little they eat. The problem was that there was no way to circumvent the underlying factors that cause excess body fat… until now! As you are about to learn, gaining control over your body’s command signals is critical to maintaining a healthy weight.

Leptin is a hormone that tells our brain that we have consumed enough calories and can stop eating. Leptin also induces a process whereby fat stored in cells is broken down. As we age, our cells (including the appetite control center in our brains) become “leptin resistant.” This means that leptin is unable to effectively regulate body weight.

Adult-onset weight gain is characterized by the enlargement of existing adipocytes (fat cells) that store too much fat. The size of fat cells is controlled by gene transcription factors. Fat cell size is closely related with adiponectin expression — with reduced adiponectin expression in larger fat cells. In addition, gene transcription factors help regulate adiponectin, and this crucial hormone is critical for supporting insulin sensitivity.